Transient antiretroviral therapy selecting for common HIV-1 mutations substantially accelerates the appearance of rare mutations
<p>Abstract</p> <p>Background</p> <p>Highly selective antiretroviral (ARV) regimens such as single dose nevirapine (NVP) used for prevention of mother to child transmission (PMTCT) in resource-limited settings produce transient increases in otherwise marginal subpopulat...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
BMC
2008-11-01
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Series: | Theoretical Biology and Medical Modelling |
Online Access: | http://www.tbiomed.com/content/5/1/25 |