Transient antiretroviral therapy selecting for common HIV-1 mutations substantially accelerates the appearance of rare mutations

<p>Abstract</p> <p>Background</p> <p>Highly selective antiretroviral (ARV) regimens such as single dose nevirapine (NVP) used for prevention of mother to child transmission (PMTCT) in resource-limited settings produce transient increases in otherwise marginal subpopulat...

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Bibliographic Details
Main Authors: Shiri Tinevimbo, Welte Alex
Format: Article
Language:English
Published: BMC 2008-11-01
Series:Theoretical Biology and Medical Modelling
Online Access:http://www.tbiomed.com/content/5/1/25