Insulin-like growth factor 1 (IGF-1) enhances the protein expression of CFTR.

Low levels of insulin-like growth factor 1 (IGF-1) have been observed in the serum of cystic fibrosis (CF) patients. However, the effects of low serum IGF-1 on the cystic fibrosis transmembrane conductance regulator (CFTR), whose defective function is the primary cause of cystic fibrosis, have not b...

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Bibliographic Details
Main Authors: Ha Won Lee, Jie Cheng, Olga Kovbasnjuk, Mark Donowitz, William B Guggino
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3610909?pdf=render