CNS relapse of childhood ALL: More than meets the eye

CNS relapse of childhood ALL: More than meets the eye

Relapse of childhood leukemia has protean manifestations. Bone marrow/central nervous system (CNS) and testis are the typical locations of relapse in acute lymphoblastic leukemia (ALL). Infrequently, the disease may relapse at atypical sites with unusual clinical features. In this communication, we...

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Bibliographic Details
Main Authors: Pritam Singha Roy, Arundhati Banerjee, Manjul Tripathi, Renu Suthar, Amita Trehan
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:Pediatric Hematology Oncology Journal
Subjects:
Relapse
CNS
Acute lymphoblastic leukemia
Online Access:http://www.sciencedirect.com/science/article/pii/S2468124521000176
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spelling doaj-35277014ac9044eebf44f1c6d607c6bd2021-06-17T04:48:26ZengElsevierPediatric Hematology Oncology Journal2468-12452021-06-01628487CNS relapse of childhood ALL: More than meets the eyePritam Singha Roy0Arundhati Banerjee1Manjul Tripathi2Renu Suthar3Amita Trehan4Pediatric Hematology-Oncology Unit, Postgraduate Institute of Medical Education and Research, Chandigarh, IndiaPediatric Neurology Unit, Advanced Pediatrics Center, Department of Pediatrics, Postgraduate Institute of Medical Education and Research, Chandigarh, IndiaDepartment of Neurosurgery, Postgraduate Institute of Medical Education and Research, Chandigarh, IndiaPediatric Neurology Unit, Advanced Pediatrics Center, Department of Pediatrics, Postgraduate Institute of Medical Education and Research, Chandigarh, IndiaPediatric Hematology-Oncology Unit, Postgraduate Institute of Medical Education and Research, Chandigarh, India; Corresponding author. Hematology-Oncology unit, Dept. of Pediatrics, Advanced Pediatrics Center, Postgraduate Institute of Medical Education and Research, Chandigarh, India.Relapse of childhood leukemia has protean manifestations. Bone marrow/central nervous system (CNS) and testis are the typical locations of relapse in acute lymphoblastic leukemia (ALL). Infrequently, the disease may relapse at atypical sites with unusual clinical features. In this communication, we present two cases of CNS relapse of ALL, who presented with unique clinical characteristics, the relapse of leukemia masquerading acute demyelinating polyradiculopathy in one patient and with flaccid quadriplegia in the second case.http://www.sciencedirect.com/science/article/pii/S2468124521000176RelapseCNSAcute lymphoblastic leukemia
collection DOAJ
language English
format Article
sources DOAJ
author Pritam Singha Roy
Arundhati Banerjee
Manjul Tripathi
Renu Suthar
Amita Trehan
spellingShingle Pritam Singha Roy
Arundhati Banerjee
Manjul Tripathi
Renu Suthar
Amita Trehan
CNS relapse of childhood ALL: More than meets the eye
Pediatric Hematology Oncology Journal
Relapse
CNS
Acute lymphoblastic leukemia
author_facet Pritam Singha Roy
Arundhati Banerjee
Manjul Tripathi
Renu Suthar
Amita Trehan
author_sort Pritam Singha Roy
title CNS relapse of childhood ALL: More than meets the eye
title_short CNS relapse of childhood ALL: More than meets the eye
title_full CNS relapse of childhood ALL: More than meets the eye
title_fullStr CNS relapse of childhood ALL: More than meets the eye
title_full_unstemmed CNS relapse of childhood ALL: More than meets the eye
title_sort cns relapse of childhood all: more than meets the eye
publisher Elsevier
series Pediatric Hematology Oncology Journal
issn 2468-1245
publishDate 2021-06-01
description Relapse of childhood leukemia has protean manifestations. Bone marrow/central nervous system (CNS) and testis are the typical locations of relapse in acute lymphoblastic leukemia (ALL). Infrequently, the disease may relapse at atypical sites with unusual clinical features. In this communication, we present two cases of CNS relapse of ALL, who presented with unique clinical characteristics, the relapse of leukemia masquerading acute demyelinating polyradiculopathy in one patient and with flaccid quadriplegia in the second case.
topic Relapse
CNS
Acute lymphoblastic leukemia
url http://www.sciencedirect.com/science/article/pii/S2468124521000176
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AT arundhatibanerjee cnsrelapseofchildhoodallmorethanmeetstheeye
AT manjultripathi cnsrelapseofchildhoodallmorethanmeetstheeye
AT renusuthar cnsrelapseofchildhoodallmorethanmeetstheeye
AT amitatrehan cnsrelapseofchildhoodallmorethanmeetstheeye
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