Influence of DNMT3A R882 mutations on AML prognosis determined by the allele ratio in Chinese patients

Influence of DNMT3A R882 mutations on AML prognosis determined by the allele ratio in Chinese patients

Abstract Background The influence of DNMT3A R882 mutations on adult acute myeloid leukemia (AML) prognosis is still controversial presently. The influence of R882 allele ratio on drug response and prognosis of AML is unknown yet. Besides, it is obscure whether anthracyclines are involved in chemores...

Full description

Bibliographic Details
Main Authors: Xiao-Qing Yuan, Peng Chen, Yin-Xiao Du, Ke-Wei Zhu, Dao-Yu Zhang, Han Yan, Han Liu, Yan-Ling Liu, Shan Cao, Gan Zhou, Hui Zeng, Shu-Ping Chen, Xie-Lan Zhao, Jing Yang, Wen-Jing Zeng, Xiao-Ping Chen
Format: Article
Language:English
Published: BMC 2019-07-01
Series:Journal of Translational Medicine
Subjects:
Acute myeloid leukemia
DNMT3A
R882 mutations
Allele ratio
Prognosis
Aclarubicin
Online Access:http://link.springer.com/article/10.1186/s12967-019-1959-3

Internet

http://link.springer.com/article/10.1186/s12967-019-1959-3

Similar Items