A comparative study of human TLR 7/8 stimulatory trimer compositions in influenza A viral genomes.

BACKGROUND: Variation in the genomes of single-stranded RNA viruses affects their infectivity and pathogenicity in two ways. First, viral genome sequence variations lead to changes in viral protein sequences and activities. Second, viral genome sequence variation produces diversity at the level of n...

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Bibliographic Details
Main Authors: Chu-Wen Yang, Sy-Mien Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3281872?pdf=render