Simple binary segmentation frameworks for identifying variation in DNA copy number

<p>Abstract</p> <p>Background</p> <p>Variation in DNA copy number, due to gains and losses of chromosome segments, is common. A first step for analyzing DNA copy number data is to identify amplified or deleted regions in individuals. To locate such regions, we propose a...

Full description

Bibliographic Details
Main Author: Yang Tae Young
Format: Article
Language:English
Published: BMC 2012-10-01
Series:BMC Bioinformatics
Subjects:
Online Access:http://www.biomedcentral.com/1471-2105/13/277