Novel Furanoid α-Substitued α-Amino Acid as a Potent Turn Mimic in Peptide Synthesis

Novel Furanoid α-Substitued α-Amino Acid as a Potent Turn Mimic in Peptide Synthesis

A stereoselective approach has been developed to the new sugar amino acid and potential potent turn mimic 5-O-(tert-butyldimethylsilyl)-3-deoxy-1,2-O- isopropylidene-3-methoxycarbonylamino-α-D-xylofuranose 3-C-carboxylic acid (12), via the [3,3]-sigmatropic rearrangement of allylic thiocyanates (...

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Bibliographic Details
Main Authors: Jana Raschmanová, Jozef Gonda, Miroslava Martinková
Format: Article
Language:English
Published: MDPI AG 2006-07-01
Series:Molecules
Subjects:
Sugar amino acids
stereoselectivity
sigmatropic rearrangement
carbohydrate-based mimetics
peptidomimetic
β-turn mimic
Online Access:http://www.mdpi.com/1420-3049/11/7/564/

Internet

http://www.mdpi.com/1420-3049/11/7/564/

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