“Hepatic toxicity by methotrexate with weekly single doses associated with folic acid in rheumatoid and psoriatic arthritis. What is its real frequency?”

“Hepatic toxicity by methotrexate with weekly single doses associated with folic acid in rheumatoid and psoriatic arthritis. What is its real frequency?”

Introduction and Objectives: Liver injury caused by methotrexate (MTX) has mostly been investigated without applying criteria for the assessment of causality of drug induced liver injury (DILI). Hence, the existence of DILI by MTX in many cases is debatable. This study aimed to describe the frequenc...

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Bibliographic Details
Main Authors: Daniel S. García, Etel I. Saturansky, Daniel Poncino, Yamila Martínez-Artola, Silvia Rosenberg, Gloria Abritta, Carlos Ascimani-Peña, Amerys Cravero
Format: Article
Language:English
Published: Elsevier 2019-09-01
Series:Annals of Hepatology
Subjects:
Methotrexate
Drug-induced liver injury
Hepatotoxicity
Rheumatoid arthritis
Psoriatic arthritis
Online Access:http://www.sciencedirect.com/science/article/pii/S1665268119300742

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