Contribution of Mitochondrial DNA Variation to Chronic Disease in East Asian Populations

Contribution of Mitochondrial DNA Variation to Chronic Disease in East Asian Populations

Mitochondria are the main producers of energy in eukaryotic cells. Mitochondrial dysfunction is associated with specific mitochondrial DNA (mtDNA) variations (haplogroups), and these variations can contribute to human disease. East Asian populations show enrichment of many mitochondrial haplogroups,...

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Bibliographic Details
Main Authors: Dayan Sun, Yang Wei, Hong-Xiang Zheng, Li Jin, Jiucun Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Molecular Biosciences
Subjects:
mitochondrial DNA
variation
haplogroup
chronic disease
East Asian
Online Access:https://www.frontiersin.org/article/10.3389/fmolb.2019.00128/full

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