Cost of Pediatric Visceral Leishmaniasis Care in Morocco.

BACKGROUND:Visceral leishmaniasis (VL) is a neglected parasitic disease that is fatal if left untreated. VL is endemic in Morocco and other countries in North Africa were it mainly affects children from rural areas. In Morocco, the direct observation of Leishmania parasites in bone marrow aspirates...

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Main Authors: Nabil Tachfouti, Adil Najdi, Sergi Alonso, Elisa Sicuri, Abderahmane Laamrani El Idrissi, Chakib Nejjari, Albert Picado
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4892465?pdf=render
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spelling doaj-35195ac4f7ea4cf7a398c20596de11e42020-11-24T21:50:24ZengPublic Library of Science (PLoS)PLoS ONE1932-62032016-01-01116e015548210.1371/journal.pone.0155482Cost of Pediatric Visceral Leishmaniasis Care in Morocco.Nabil TachfoutiAdil NajdiSergi AlonsoElisa SicuriAbderahmane Laamrani El IdrissiChakib NejjariAlbert PicadoBACKGROUND:Visceral leishmaniasis (VL) is a neglected parasitic disease that is fatal if left untreated. VL is endemic in Morocco and other countries in North Africa were it mainly affects children from rural areas. In Morocco, the direct observation of Leishmania parasites in bone marrow aspirates and serological tests are used to diagnose VL. Glucantime is the first line of treatment. The objective of this study was to report the costs associated to standard clinical management of pediatric VL from the provider perspective in Morocco. As a secondary objective we described the current clinical practices and the epidemiological characteristics of pediatric VL patients. METHODS:From March to June 2014 we conducted a survey in eight hospitals treating pediatric VL patients in Morocco. A pro-forma was used to collect demographic, clinical and management data from medical records. We specifically collected data on VL diagnosis and treatment. We also estimated the days of hospitalization and the time to start VL treatment. Costs were estimated by multiplying the use of resources in terms of number of days in hospital, tests performed and drugs provided by the official prices. For patients receiving part of their treatment at Primary Health Centers (PHC) we estimated the cost of administering the Glucantime as outpatient. We calculated the median cost per VL patient. We also estimated the cost of managing a VL case when different treatment strategies were applied: inpatient and outpatient. RESULTS:We obtained data from 127 VL patients. The median total cost per pediatric VL case in Morocco is 520 US$. The cost in hospitals applying an outpatient strategy is significantly lower (307 US$) than hospitals keeping the patients for the whole treatment (636 US$). However the outpatient strategy is not yet recommended as VL treatment for children in the Moroccan guidelines. VL diagnosis and treatment regimens should be standardized following the current guidelines in Morocco.http://europepmc.org/articles/PMC4892465?pdf=render
collection DOAJ
language English
format Article
sources DOAJ
author Nabil Tachfouti
Adil Najdi
Sergi Alonso
Elisa Sicuri
Abderahmane Laamrani El Idrissi
Chakib Nejjari
Albert Picado
spellingShingle Nabil Tachfouti
Adil Najdi
Sergi Alonso
Elisa Sicuri
Abderahmane Laamrani El Idrissi
Chakib Nejjari
Albert Picado
Cost of Pediatric Visceral Leishmaniasis Care in Morocco.
PLoS ONE
author_facet Nabil Tachfouti
Adil Najdi
Sergi Alonso
Elisa Sicuri
Abderahmane Laamrani El Idrissi
Chakib Nejjari
Albert Picado
author_sort Nabil Tachfouti
title Cost of Pediatric Visceral Leishmaniasis Care in Morocco.
title_short Cost of Pediatric Visceral Leishmaniasis Care in Morocco.
title_full Cost of Pediatric Visceral Leishmaniasis Care in Morocco.
title_fullStr Cost of Pediatric Visceral Leishmaniasis Care in Morocco.
title_full_unstemmed Cost of Pediatric Visceral Leishmaniasis Care in Morocco.
title_sort cost of pediatric visceral leishmaniasis care in morocco.
publisher Public Library of Science (PLoS)
series PLoS ONE
issn 1932-6203
publishDate 2016-01-01
description BACKGROUND:Visceral leishmaniasis (VL) is a neglected parasitic disease that is fatal if left untreated. VL is endemic in Morocco and other countries in North Africa were it mainly affects children from rural areas. In Morocco, the direct observation of Leishmania parasites in bone marrow aspirates and serological tests are used to diagnose VL. Glucantime is the first line of treatment. The objective of this study was to report the costs associated to standard clinical management of pediatric VL from the provider perspective in Morocco. As a secondary objective we described the current clinical practices and the epidemiological characteristics of pediatric VL patients. METHODS:From March to June 2014 we conducted a survey in eight hospitals treating pediatric VL patients in Morocco. A pro-forma was used to collect demographic, clinical and management data from medical records. We specifically collected data on VL diagnosis and treatment. We also estimated the days of hospitalization and the time to start VL treatment. Costs were estimated by multiplying the use of resources in terms of number of days in hospital, tests performed and drugs provided by the official prices. For patients receiving part of their treatment at Primary Health Centers (PHC) we estimated the cost of administering the Glucantime as outpatient. We calculated the median cost per VL patient. We also estimated the cost of managing a VL case when different treatment strategies were applied: inpatient and outpatient. RESULTS:We obtained data from 127 VL patients. The median total cost per pediatric VL case in Morocco is 520 US$. The cost in hospitals applying an outpatient strategy is significantly lower (307 US$) than hospitals keeping the patients for the whole treatment (636 US$). However the outpatient strategy is not yet recommended as VL treatment for children in the Moroccan guidelines. VL diagnosis and treatment regimens should be standardized following the current guidelines in Morocco.
url http://europepmc.org/articles/PMC4892465?pdf=render
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