Adaptive molecular evolution of the Major Histocompatibility Complex genes, <it>DRA </it>and <it>DQA</it>, in the genus <it>Equus</it>

<p>Abstract</p> <p>Background</p> <p>Major Histocompatibility Complex (MHC) genes are central to vertebrate immune response and are believed to be under balancing selection by pathogens. This hypothesis has been supported by observations of extremely high polymorphism,...

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Bibliographic Details
Main Authors: Getz Wayne M, Kamath Pauline L
Format: Article
Language:English
Published: BMC 2011-05-01
Series:BMC Evolutionary Biology
Online Access:http://www.biomedcentral.com/1471-2148/11/128