Anticancer and Anti-Inflammatory Activities of Some New Pyrazolo[3,4-b]pyrazines

Anticancer and Anti-Inflammatory Activities of Some New Pyrazolo[3,4-b]pyrazines

New derivatives of pyrazolo[3,4-b]pyrazines and related heterocycles were synthesized using 5-amino-3-methyl-4-nitroso-1-phenyl-pyrazole (1) as a starting material. The 5-acetyl derivative 15 was shown to be a useful key intermediate for the synthesis of several derivatives of pyrazolopyrazines. Som...

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Bibliographic Details
Main Authors: Hussein El-Kashef, Talaat El-Emary, Pierre Verhaeghe, Patrice Vanelle, Maha Samy
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:Molecules
Subjects:
pyrazolo[3,4-b]pyrazines
o-aminonitrosopyrazole
anticancer
anti-inflammatory
anti-breast cancer
Online Access:http://www.mdpi.com/1420-3049/23/10/2657

Internet

http://www.mdpi.com/1420-3049/23/10/2657

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