Cysteine-rich secretory protein-3 (CRISP3) is strongly up-regulated in prostate carcinomas with the TMPRSS2-ERG fusion gene.

Cysteine-rich secretory protein-3 (CRISP3) is strongly up-regulated in prostate carcinomas with the TMPRSS2-ERG fusion gene.

A large percentage of prostate cancers harbor TMPRSS2-ERG gene fusions, leading to aberrant overexpression of the transcription factor ERG. The target genes deregulated by this rearrangement, however, remain mostly unknown. To address this subject we performed genome-wide mRNA expression analysis on...

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Bibliographic Details
Main Authors: Franclim R Ribeiro, Paula Paulo, Vera L Costa, João D Barros-Silva, João Ramalho-Carvalho, Carmen Jerónimo, Rui Henrique, Guro E Lind, Rolf I Skotheim, Ragnhild A Lothe, Manuel R Teixeira
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21814574/?tool=EBI

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