NLRP3 inflammasome as a novel target for docosahexaenoic acid metabolites to abrogate glomerular injury[S]

NLRP3 inflammasome as a novel target for docosahexaenoic acid metabolites to abrogate glomerular injury[S]

The nucleotide-binding oligomerization domain-like receptor containing pyrin domain 3 (NLRP3) inflammasome has been implicated in podocyte injury and glomerular sclerosis during hyperhomocysteinemia (hHcys). However, it remains unclear whether the NLRP3 inflammasome can be a therapeutic target for t...

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Bibliographic Details
Main Authors: Guangbi Li, Zhida Chen, Owais M. Bhat, Qinghua Zhang, Justine M. Abais-Battad, Sabena M. Conley, Joseph K. Ritter, Pin-Lan Li
Format: Article
Language:English
Published: Elsevier 2017-06-01
Series:Journal of Lipid Research
Subjects:
inflammation
lipid mediators
ω-3 fatty acid
lipoxygenase
kidney
podocyte
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520310014

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