Improving cytosolic aspartate biosynthesis increases glucoamylase production in Aspergillus niger under oxygen limitation

Improving cytosolic aspartate biosynthesis increases glucoamylase production in Aspergillus niger under oxygen limitation

Abstract Background Glucoamylase is one of the most industrially applied enzymes, produced by Aspergillus species, like Aspergillus niger. Compared to the traditional ways of process optimization, the metabolic engineering strategies to improve glucoamylase production are relatively scarce. Results...

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Bibliographic Details
Main Authors: Weiqiang Cao, Guan Wang, Hongzhong Lu, Liming Ouyang, Ju Chu, Yufei Sui, Yingping Zhuang
Format: Article
Language:English
Published: BMC 2020-04-01
Series:Microbial Cell Factories
Subjects:
Aspergillus niger
Glucoamylase
Limited amino acids
Gene overexpression
Multi-omics study
Online Access:http://link.springer.com/article/10.1186/s12934-020-01340-1

Internet

http://link.springer.com/article/10.1186/s12934-020-01340-1

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