Adoptive T cell therapy targeting CD1 and MR1

Adoptive T cell immunotherapy has demonstrated clinically relevant efficacy in treating malignant and infectious diseases. However, much of these therapies have been focused on enhancing, or generating de novo, effector functions of conventional T cells recognizing HLA molecules. Given the heterogen...

Full description

Bibliographic Details
Main Authors: Tingxi eGuo, Kenji eChamoto, Naoto eHirano
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-05-01
Series:Frontiers in Immunology
Subjects:
NKT
MR1
CD1
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00247/full