Somatic copy number alterations are associated with EGFR amplification and shortened survival in patients with primary glioblastoma

Glioblastoma (GBM) is the most common malignant primary tumor of the central nervous system. With no effective therapy, the prognosis for patients is terrible poor. It is highly heterogeneous and EGFR amplification is its most frequent molecular alteration.In this light, we aimed to examine the gene...

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Bibliographic Details
Main Authors: Lisandra Muñoz-Hidalgo, Teresa San-Miguel, Javier Megías, Daniel Monleón, Lara Navarro, Pedro Roldán, Miguel Cerdá-Nicolás, Concha López-Ginés
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558619302428