CRISPR/Cas12a Mediated Genome Editing Enhances Bombyx mori Resistance to BmNPV

CRISPR/Cas12a Mediated Genome Editing Enhances Bombyx mori Resistance to BmNPV

CRISPR/Cas12a (Cpf1) is a single RNA-guided endonuclease that provides new opportunities for targeted genome engineering through the CRISPR/Cas9 system. Only AsCas12a has been developed for insect genome editing, and the novel Cas12a orthologs nucleases and editing efficiency require more study on i...

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Bibliographic Details
Main Authors: Zhanqi Dong, Qi Qin, Zhigang Hu, Xinling Zhang, Jianghao Miao, Liang Huang, Peng Chen, Cheng Lu, Minhui Pan
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
CRISPR/Cas12a
genome editing
antiviral therapy
Bombyx mori
BmNPV
Online Access:https://www.frontiersin.org/article/10.3389/fbioe.2020.00841/full

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