Modeling Electrophysiological Coupling and Fusion between Human Mesenchymal Stem Cells and Cardiomyocytes.

Human mesenchymal stem cell (hMSC) delivery has demonstrated promise in preclinical and clinical trials for myocardial infarction therapy; however, broad acceptance is hindered by limited understanding of hMSC-human cardiomyocyte (hCM) interactions. To better understand the electrophysiological cons...

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Bibliographic Details
Main Authors: Joshua Mayourian, Ruben M Savizky, Eric A Sobie, Kevin D Costa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-07-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC4959759?pdf=render