Origanum majorana Ethanolic Extract Promotes Colorectal Cancer Cell Death by Triggering Abortive Autophagy and Activation of the Extrinsic Apoptotic Pathway

Origanum majorana Ethanolic Extract Promotes Colorectal Cancer Cell Death by Triggering Abortive Autophagy and Activation of the Extrinsic Apoptotic Pathway

Colorectal cancer is considered as the third leading cause of cancer death. In the present study, we investigated the potential anticancer effect and the molecular mechanism of Origanum majorana ethanolic extract (OME) against human colorectal cancer cells. We showed that OME exhibited strong anti-p...

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Bibliographic Details
Main Authors: Nehla Benhalilou, Halima Alsamri, Aysha Alneyadi, Khawlah Athamneh, Asma Alrashedi, Nedaa Altamimi, Yusra Al Dhaheri, Ali H. Eid, Rabah Iratni
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Oncology
Subjects:
colon cancer
abortive autophagy
apoptosis
DNA damage
Origanum majorana
HPLC-MS
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.00795/full

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