A stochastic view on surface inhomogeneity of nanoparticles

Determining the spatial arrangement of molecules on a nanoparticle’s surface is key to understanding its interactions. Here, the authors use dSTORM imaging and probabilistic modelling to map the distribution of fluorophores on a nanoparticle, finding that ligand coverage is heterogeneous and highly...

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Main Authors:	R. A. J. Post, D. van der Zwaag, G. Bet, S. P. W. Wijnands, L. Albertazzi, E. W. Meijer, R. W. van der Hofstad
Format:	Article
Language:	English
Published:	Nature Publishing Group 2019-04-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/s41467-019-09595-y

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spelling	doaj-34cb2e14387845d899b68a5d07e07b572021-05-11T11:34:45ZengNature Publishing GroupNature Communications2041-17232019-04-0110111110.1038/s41467-019-09595-yA stochastic view on surface inhomogeneity of nanoparticlesR. A. J. Post0D. van der Zwaag1G. Bet2S. P. W. Wijnands3L. Albertazzi4E. W. Meijer5R. W. van der Hofstad6Institute of Complex Molecular Systems, Eindhoven University of TechnologyInstitute of Complex Molecular Systems, Eindhoven University of TechnologyInstitute of Complex Molecular Systems, Eindhoven University of TechnologyInstitute of Complex Molecular Systems, Eindhoven University of TechnologyInstitute of Complex Molecular Systems, Eindhoven University of TechnologyInstitute of Complex Molecular Systems, Eindhoven University of TechnologyInstitute of Complex Molecular Systems, Eindhoven University of TechnologyDetermining the spatial arrangement of molecules on a nanoparticle’s surface is key to understanding its interactions. Here, the authors use dSTORM imaging and probabilistic modelling to map the distribution of fluorophores on a nanoparticle, finding that ligand coverage is heterogeneous and highly variable between individual particles.https://doi.org/10.1038/s41467-019-09595-y
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	R. A. J. Post D. van der Zwaag G. Bet S. P. W. Wijnands L. Albertazzi E. W. Meijer R. W. van der Hofstad
spellingShingle	R. A. J. Post D. van der Zwaag G. Bet S. P. W. Wijnands L. Albertazzi E. W. Meijer R. W. van der Hofstad A stochastic view on surface inhomogeneity of nanoparticles Nature Communications
author_facet	R. A. J. Post D. van der Zwaag G. Bet S. P. W. Wijnands L. Albertazzi E. W. Meijer R. W. van der Hofstad
author_sort	R. A. J. Post
title	A stochastic view on surface inhomogeneity of nanoparticles
title_short	A stochastic view on surface inhomogeneity of nanoparticles
title_full	A stochastic view on surface inhomogeneity of nanoparticles
title_fullStr	A stochastic view on surface inhomogeneity of nanoparticles
title_full_unstemmed	A stochastic view on surface inhomogeneity of nanoparticles
title_sort	stochastic view on surface inhomogeneity of nanoparticles
publisher	Nature Publishing Group
series	Nature Communications
issn	2041-1723
publishDate	2019-04-01
description	Determining the spatial arrangement of molecules on a nanoparticle’s surface is key to understanding its interactions. Here, the authors use dSTORM imaging and probabilistic modelling to map the distribution of fluorophores on a nanoparticle, finding that ligand coverage is heterogeneous and highly variable between individual particles.
url	https://doi.org/10.1038/s41467-019-09595-y
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A stochastic view on surface inhomogeneity of nanoparticles

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