The Cellular DExD/H-Box RNA Helicase UAP56 Co-localizes With the Influenza A Virus NS1 Protein

The Cellular DExD/H-Box RNA Helicase UAP56 Co-localizes With the Influenza A Virus NS1 Protein

UAP56, a member of the DExD/H-box RNA helicase family, is essential for pre-mRNA splicing and mRNA export in eukaryotic cells. In influenza A virus-infected cells, UAP56 mediates viral mRNA nuclear export, facilitates viral ribonucleoprotein complex formation through direct interaction with the vira...

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Bibliographic Details
Main Authors: Shiho Chiba, Lindsay Hill-Batorski, Gabriele Neumann, Yoshihiro Kawaoka
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Microbiology
Subjects:
influenza A virus
UAP56
influenza A NS1
nuclear localization
host factors
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.02192/full

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