Characterization of human CD39+ Th17 cells with suppressor activity and modulation in inflammatory bowel disease.

Characterization of human CD39+ Th17 cells with suppressor activity and modulation in inflammatory bowel disease.

Induced regulatory T-cells (iT-reg) and T helper type 17 (Th17) in the mouse share common CD4 progenitor cells and exhibit overlapping phenotypic and functional features. Here, we show that human Th17 cells endowed with suppressor activity (supTh17) can be derived following exposure of iT-reg popula...

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Bibliographic Details
Main Authors: Maria Serena Longhi, Alan Moss, Aiping Bai, Yan Wu, Huang Huang, Adam Cheifetz, Francisco J Quintana, Simon C Robson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3914873?pdf=render

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