Combined prime-boost vaccination against tick-borne encephalitis (TBE) using a recombinant vaccinia virus and a bacterial plasmid both expressing TBE virus non-structural NS1 protein

<p>Abstract</p> <p>Background</p> <p>Heterologous prime-boost immunization protocols using different gene expression systems have proven to be successful tools in protecting against various diseases in experimental animal models. The main reason for using this approach...

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Bibliographic Details
Main Authors: Zakharova LG, Khoretonenko MV, Timofeev AV, Aleshin SE, Pashvykina GV, Stephenson JR, Shneider AM, Altstein AD
Format: Article
Language:English
Published: BMC 2005-08-01
Series:BMC Microbiology
Online Access:http://www.biomedcentral.com/1471-2180/5/45