Inhibition of reactive gliosis prevents neovascular growth in the mouse model of oxygen-induced retinopathy.

Retinal neovascularization (NV) is a major cause of blindness in ischemic retinopathies. Previous investigations have indicated that ischemia upregulates GFAP and PDGF-B expression. GFAP overexpression is a hallmark of reactive gliosis (RG), which is the major pathophysiological feature of retinal d...

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Bibliographic Details
Main Authors: Michael DeNiro, Falah H Al-Mohanna, Futwan A Al-Mohanna
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21779402/?tool=EBI

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