A Facile and Catalyst-Free Microwave-Promoted Multicomponent Reaction for the Synthesis of Functionalised 1,4-Dihydropyridines With Superb Selectivity and Yields

A Facile and Catalyst-Free Microwave-Promoted Multicomponent Reaction for the Synthesis of Functionalised 1,4-Dihydropyridines With Superb Selectivity and Yields

We report a highly efficient green protocol for developing a novel library of 1,2,4-triazole-tagged 1,4-dihydropyridine analogs through the one-pot process from the four-component fusion of the 1H-1,2,4-triazol-3-amine with different chosen aldehydes, diethyl acetylenedicarboxylate, and active methy...

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Bibliographic Details
Main Authors: Nagaraju Kerru, Suresh Maddila, Sreekantha B. Jonnalagadda
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Chemistry
Subjects:
microwave irradiation
multi-component reaction
aqueous medium
1
4-dihydropyridine
one-pot method
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2021.638832/full

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