Enhanced Mortality to Metastatic Bladder Cancer Cell Line MB49 in Vasoactive Intestinal Peptide Gene Knockout Mice

Enhanced Mortality to Metastatic Bladder Cancer Cell Line MB49 in Vasoactive Intestinal Peptide Gene Knockout Mice

To identify if the absence of the vasoactive intestinal peptide (VIP) gene enhances susceptibility to death from metastatic bladder cancer, two strains of mice were injected with MB49 murine bladder cancer cells. The growth and spread of the cancer was measured over a period of 4 weeks in C57BL/6 mi...

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Bibliographic Details
Main Authors: Niely Mirsaidi, Matthew P. Burns, Steve A. McClain, Edward Forsyth, Jonathan Li, Brittany Dukes, David Lin, Roxanna Nahvi, Jheison Giraldo, Megan Patton, Ping Wang, Ke Lin, Edmund Miller, Timothy Ratliff, Sayyed Hamidi, Scott Crist, Ken-Ichi Takemaru, Anthony Szema
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-08-01
Series:Frontiers in Endocrinology
Subjects:
vasoactive intestinal peptide gene knockout mice
MB49 murine bladder cancer
mortality
metastases
vasoactive intestinal peptide
Online Access:http://journal.frontiersin.org/article/10.3389/fendo.2017.00162/full

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http://journal.frontiersin.org/article/10.3389/fendo.2017.00162/full

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