Intestinal NADPH oxidase 2 activity increases in a neonatal rat model of necrotizing enterocolitis.

Necrotizing enterocolitis (NEC) is a complication of prematurity. The etiology is unknown, but is related to enteral feeding, ischemia, infection, and inflammation. Reactive oxygen species production, most notably superoxide, increases in NEC. NADPH oxidase (NOX) generates superoxide, but its activi...

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Bibliographic Details
Main Authors: Scott R Welak, Rebecca M Rentea, Ru-Jeng Teng, Nathan Heinzerling, Ben Biesterveld, Jennifer L Liedel, Kirkwood A Pritchard, Katherine M Fredrich, David M Gourlay
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4269454?pdf=render