Evaluation of the efficacy and safety of endovascular management for transplant renal artery stenosis

OBJECTIVES: To evaluate the safety and efficacy of endovascular intervention with angioplasty and stent placement in patients with transplant renal artery stenosis. METHODS: All patients diagnosed with transplant renal artery stenosis and graft dysfunction or resistant systemic hypertension who und...

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Main Authors: Leonardo G.M. Valle, Rafael N. Cavalcante, Joaquim M. Motta-Leal-Filho, Breno B. Affonso, Francisco L. Galastri, Marisa P. Doher, Nadia K. Guimarães-Souza, Ana K.N. Cavalcanti, Rodrigo G. Garcia, Álvaro Pacheco-Silva, Felipe Nasser
Format: Article
Language:English
Published: Faculdade de Medicina / USP
Series:Clinics
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322017001200773&lng=en&tlng=en
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spelling doaj-34558d4083a1475fb775888d1c4f3d932020-11-25T02:05:47ZengFaculdade de Medicina / USPClinics1980-5322721277377910.6061/clinics/2017(12)09S1807-59322017001200773Evaluation of the efficacy and safety of endovascular management for transplant renal artery stenosisLeonardo G.M. ValleRafael N. CavalcanteJoaquim M. Motta-Leal-FilhoBreno B. AffonsoFrancisco L. GalastriMarisa P. DoherNadia K. Guimarães-SouzaAna K.N. CavalcantiRodrigo G. GarciaÁlvaro Pacheco-SilvaFelipe NasserOBJECTIVES: To evaluate the safety and efficacy of endovascular intervention with angioplasty and stent placement in patients with transplant renal artery stenosis. METHODS: All patients diagnosed with transplant renal artery stenosis and graft dysfunction or resistant systemic hypertension who underwent endovascular treatment with stenting from February 2011 to April 2016 were included in this study. The primary endpoint was clinical success, and the secondary endpoints were technical success, complication rate and stent patency. RESULTS: Twenty-four patients with transplant renal artery stenosis underwent endovascular treatment, and three of them required reinterventions, resulting in a total of 27 procedures. The clinical success rate was 100%. All graft dysfunction patients showed decreased serum creatinine levels and improved estimated glomerular filtration rates and creatinine levels. Patients with high blood pressure also showed improved control of systemic blood pressure and decreased use of antihypertensive drugs. The technical success rate of the procedure was 97%. Primary patency and assisted primary patency rates at one year were 90.5% and 100%, respectively. The mean follow-up time of patients was 794.04 days after angioplasty. CONCLUSION: Angioplasty with stent placement for the treatment of transplant renal artery stenosis is a safe and effective technique with good results in both the short and long term.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322017001200773&lng=en&tlng=enTransplant Renal Artery StenosisEndovascular TreatmentStentingRenal Transplantation
collection DOAJ
language English
format Article
sources DOAJ
author Leonardo G.M. Valle
Rafael N. Cavalcante
Joaquim M. Motta-Leal-Filho
Breno B. Affonso
Francisco L. Galastri
Marisa P. Doher
Nadia K. Guimarães-Souza
Ana K.N. Cavalcanti
Rodrigo G. Garcia
Álvaro Pacheco-Silva
Felipe Nasser
spellingShingle Leonardo G.M. Valle
Rafael N. Cavalcante
Joaquim M. Motta-Leal-Filho
Breno B. Affonso
Francisco L. Galastri
Marisa P. Doher
Nadia K. Guimarães-Souza
Ana K.N. Cavalcanti
Rodrigo G. Garcia
Álvaro Pacheco-Silva
Felipe Nasser
Evaluation of the efficacy and safety of endovascular management for transplant renal artery stenosis
Clinics
Transplant Renal Artery Stenosis
Endovascular Treatment
Stenting
Renal Transplantation
author_facet Leonardo G.M. Valle
Rafael N. Cavalcante
Joaquim M. Motta-Leal-Filho
Breno B. Affonso
Francisco L. Galastri
Marisa P. Doher
Nadia K. Guimarães-Souza
Ana K.N. Cavalcanti
Rodrigo G. Garcia
Álvaro Pacheco-Silva
Felipe Nasser
author_sort Leonardo G.M. Valle
title Evaluation of the efficacy and safety of endovascular management for transplant renal artery stenosis
title_short Evaluation of the efficacy and safety of endovascular management for transplant renal artery stenosis
title_full Evaluation of the efficacy and safety of endovascular management for transplant renal artery stenosis
title_fullStr Evaluation of the efficacy and safety of endovascular management for transplant renal artery stenosis
title_full_unstemmed Evaluation of the efficacy and safety of endovascular management for transplant renal artery stenosis
title_sort evaluation of the efficacy and safety of endovascular management for transplant renal artery stenosis
publisher Faculdade de Medicina / USP
series Clinics
issn 1980-5322
description OBJECTIVES: To evaluate the safety and efficacy of endovascular intervention with angioplasty and stent placement in patients with transplant renal artery stenosis. METHODS: All patients diagnosed with transplant renal artery stenosis and graft dysfunction or resistant systemic hypertension who underwent endovascular treatment with stenting from February 2011 to April 2016 were included in this study. The primary endpoint was clinical success, and the secondary endpoints were technical success, complication rate and stent patency. RESULTS: Twenty-four patients with transplant renal artery stenosis underwent endovascular treatment, and three of them required reinterventions, resulting in a total of 27 procedures. The clinical success rate was 100%. All graft dysfunction patients showed decreased serum creatinine levels and improved estimated glomerular filtration rates and creatinine levels. Patients with high blood pressure also showed improved control of systemic blood pressure and decreased use of antihypertensive drugs. The technical success rate of the procedure was 97%. Primary patency and assisted primary patency rates at one year were 90.5% and 100%, respectively. The mean follow-up time of patients was 794.04 days after angioplasty. CONCLUSION: Angioplasty with stent placement for the treatment of transplant renal artery stenosis is a safe and effective technique with good results in both the short and long term.
topic Transplant Renal Artery Stenosis
Endovascular Treatment
Stenting
Renal Transplantation
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322017001200773&lng=en&tlng=en
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