TGFbeta induces apoptosis and EMT in primary mouse hepatocytes independently of <it>p53</it>, <it>p21</it><sup>Cip1 </sup>or <it>Rb </it>status

<p>Abstract</p> <p>Background</p> <p>TGFβ has pleiotropic effects that range from regulation of proliferation and apoptosis to morphological changes and epithelial-mesenchymal transition (EMT). Some evidence suggests that these effects may be interconnected. We have rec...

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Bibliographic Details
Main Authors: Harrison David J, Harland Stephen N, Bellamy Christopher O, Sheahan Sharon, Prost Sandrine
Format: Article
Language:English
Published: BMC 2008-07-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/8/191