Bcl-XL is qualitatively different from and ten times more effective than Bcl-2 when expressed in a breast cancer cell line

Bcl-XL is qualitatively different from and ten times more effective than Bcl-2 when expressed in a breast cancer cell line

<p>Abstract</p> <p>Background</p> <p>Bcl-2 and Bcl-XL are anti-apoptotic paralogues that inhibit apoptosis elicited by a wide variety of stimuli, and play critical roles in cancer development and resistance to treatment. Many clinical studies have indicated that express...

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Bibliographic Details
Main Authors: Leber Brian, Hollerbach Catherine, Zhu Weijia, Fiebig Aline A, Andrews David W
Format: Article
Language:English
Published: BMC 2006-08-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/6/213

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