Cellular Responses to Cisplatin-Induced DNA Damage

Cisplatin is one of the most effective anticancer agents widely used in the treatment of solid tumors. It is generally considered as a cytotoxic drug which kills cancer cells by damaging DNA and inhibiting DNA synthesis. How cells respond to cisplatin-induced DNA damage plays a critical role in deci...

Full description

Bibliographic Details
Main Authors: Alakananda Basu, Soumya Krishnamurthy
Format: Article
Language:English
Published: Hindawi Limited 2010-01-01
Series:Journal of Nucleic Acids
Online Access:http://dx.doi.org/10.4061/2010/201367