Interleukin-10 Protection against Lipopolysaccharide-Induced Neuro-Inflammation and Neurotoxicity in Ventral Mesencephalic Cultures

Interleukin-10 Protection against Lipopolysaccharide-Induced Neuro-Inflammation and Neurotoxicity in Ventral Mesencephalic Cultures

Interleukin (IL)-10, an anti-inflammatory cytokine, is expressed in the brain and can inhibit microglial activation. Herein, we utilized lipopolysaccharide (LPS)-induced inflammatory Parkinson’s disease (PD) cell model to determine whether microglia and astrocytes are necessary targets for IL-10 neu...

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Bibliographic Details
Main Authors: Yan Zhu, Xiao Chen, Zhan Liu, Yu-Ping Peng, Yi-Hua Qiu
Format: Article
Language:English
Published: MDPI AG 2015-12-01
Series:International Journal of Molecular Sciences
Subjects:
IL-10
LPS
Parkinson’s disease
dopaminergic neurons
microglia
astrocytes
Online Access:http://www.mdpi.com/1422-0067/17/1/25

Internet

http://www.mdpi.com/1422-0067/17/1/25

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