Radiolabeled Peptides for Cancer Imaging and Therapy: From Bench-to-Bedside

Radiolabeled peptides can deliver radiation selectively to tumors via targeting peptide receptors that are overexpressed on the surface of cancer cells. The radiation is used either for detection (imaging) or for destruction (therapy) of these tumors. The Division of Radiopharmaceutical Chemistry at...

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Main Authors: Rosalba Mansi, Melpomene Fani
Format: Article
Language:deu
Published: Swiss Chemical Society 2021-06-01
Series:CHIMIA
Subjects:
Online Access:https://www.ingentaconnect.com/contentone/scs/chimia/2021/00000075/00000006/art00007
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spelling doaj-343cb6970b6e441aa1faeb8c109cecea2021-07-16T13:28:29ZdeuSwiss Chemical SocietyCHIMIA0009-42932673-24242021-06-0175650050410.2533/chimia.2021.500Radiolabeled Peptides for Cancer Imaging and Therapy: From Bench-to-BedsideRosalba Mansi0Melpomene Fani1Division of Radiopharmaceutical Chemistry, University Hospital Basel, University of Basel, CH-4031 Basel, SwitzerlandDivision of Radiopharmaceutical Chemistry, University Hospital Basel, University of Basel, CH-4031 Basel, SwitzerlandRadiolabeled peptides can deliver radiation selectively to tumors via targeting peptide receptors that are overexpressed on the surface of cancer cells. The radiation is used either for detection (imaging) or for destruction (therapy) of these tumors. The Division of Radiopharmaceutical Chemistry at the University Hospital Basel has conducted pioneering work on the development of peptide-based radiopharmaceuticals. Our research covers the entire spectrum of such developments, from bench-to-bedside, and it is illustrated in this article by selective cases.https://www.ingentaconnect.com/contentone/scs/chimia/2021/00000075/00000006/art00007clinical translationexendin-4minigastrinsomatostatintheranostics
collection DOAJ
language deu
format Article
sources DOAJ
author Rosalba Mansi
Melpomene Fani
spellingShingle Rosalba Mansi
Melpomene Fani
Radiolabeled Peptides for Cancer Imaging and Therapy: From Bench-to-Bedside
CHIMIA
clinical translation
exendin-4
minigastrin
somatostatin
theranostics
author_facet Rosalba Mansi
Melpomene Fani
author_sort Rosalba Mansi
title Radiolabeled Peptides for Cancer Imaging and Therapy: From Bench-to-Bedside
title_short Radiolabeled Peptides for Cancer Imaging and Therapy: From Bench-to-Bedside
title_full Radiolabeled Peptides for Cancer Imaging and Therapy: From Bench-to-Bedside
title_fullStr Radiolabeled Peptides for Cancer Imaging and Therapy: From Bench-to-Bedside
title_full_unstemmed Radiolabeled Peptides for Cancer Imaging and Therapy: From Bench-to-Bedside
title_sort radiolabeled peptides for cancer imaging and therapy: from bench-to-bedside
publisher Swiss Chemical Society
series CHIMIA
issn 0009-4293
2673-2424
publishDate 2021-06-01
description Radiolabeled peptides can deliver radiation selectively to tumors via targeting peptide receptors that are overexpressed on the surface of cancer cells. The radiation is used either for detection (imaging) or for destruction (therapy) of these tumors. The Division of Radiopharmaceutical Chemistry at the University Hospital Basel has conducted pioneering work on the development of peptide-based radiopharmaceuticals. Our research covers the entire spectrum of such developments, from bench-to-bedside, and it is illustrated in this article by selective cases.
topic clinical translation
exendin-4
minigastrin
somatostatin
theranostics
url https://www.ingentaconnect.com/contentone/scs/chimia/2021/00000075/00000006/art00007
work_keys_str_mv AT rosalbamansi radiolabeledpeptidesforcancerimagingandtherapyfrombenchtobedside
AT melpomenefani radiolabeledpeptidesforcancerimagingandtherapyfrombenchtobedside
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