A redox-based electrogenetic CRISPR system to connect with and control biological information networks

Redox-responsive transcriptional regulators can enable user-specified electronic control over biological functions. Here the authors demonstrate electronic control of CRISPRa and CRISPRi using redox signalling.

Bibliographic Details
Main Authors: Narendranath Bhokisham, Eric VanArsdale, Kristina T. Stephens, Pricila Hauk, Gregory F. Payne, William E. Bentley
Format: Article
Language:English
Published: Nature Publishing Group 2020-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-16249-x
id doaj-342e464f3acf40f68405ffc01b6bffe3
record_format Article
spelling doaj-342e464f3acf40f68405ffc01b6bffe32021-05-16T11:12:03ZengNature Publishing GroupNature Communications2041-17232020-05-0111111210.1038/s41467-020-16249-xA redox-based electrogenetic CRISPR system to connect with and control biological information networksNarendranath Bhokisham0Eric VanArsdale1Kristina T. Stephens2Pricila Hauk3Gregory F. Payne4William E. Bentley5Biological Sciences Graduate Program—College of Computer, Mathematical and Natural Sciences, University of MarylandInstitute of Bioscience and Biotechnology Research, University of MarylandInstitute of Bioscience and Biotechnology Research, University of MarylandInstitute of Bioscience and Biotechnology Research, University of MarylandInstitute of Bioscience and Biotechnology Research, University of MarylandInstitute of Bioscience and Biotechnology Research, University of MarylandRedox-responsive transcriptional regulators can enable user-specified electronic control over biological functions. Here the authors demonstrate electronic control of CRISPRa and CRISPRi using redox signalling.https://doi.org/10.1038/s41467-020-16249-x
collection DOAJ
language English
format Article
sources DOAJ
author Narendranath Bhokisham
Eric VanArsdale
Kristina T. Stephens
Pricila Hauk
Gregory F. Payne
William E. Bentley
spellingShingle Narendranath Bhokisham
Eric VanArsdale
Kristina T. Stephens
Pricila Hauk
Gregory F. Payne
William E. Bentley
A redox-based electrogenetic CRISPR system to connect with and control biological information networks
Nature Communications
author_facet Narendranath Bhokisham
Eric VanArsdale
Kristina T. Stephens
Pricila Hauk
Gregory F. Payne
William E. Bentley
author_sort Narendranath Bhokisham
title A redox-based electrogenetic CRISPR system to connect with and control biological information networks
title_short A redox-based electrogenetic CRISPR system to connect with and control biological information networks
title_full A redox-based electrogenetic CRISPR system to connect with and control biological information networks
title_fullStr A redox-based electrogenetic CRISPR system to connect with and control biological information networks
title_full_unstemmed A redox-based electrogenetic CRISPR system to connect with and control biological information networks
title_sort redox-based electrogenetic crispr system to connect with and control biological information networks
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2020-05-01
description Redox-responsive transcriptional regulators can enable user-specified electronic control over biological functions. Here the authors demonstrate electronic control of CRISPRa and CRISPRi using redox signalling.
url https://doi.org/10.1038/s41467-020-16249-x
work_keys_str_mv AT narendranathbhokisham aredoxbasedelectrogeneticcrisprsystemtoconnectwithandcontrolbiologicalinformationnetworks
AT ericvanarsdale aredoxbasedelectrogeneticcrisprsystemtoconnectwithandcontrolbiologicalinformationnetworks
AT kristinatstephens aredoxbasedelectrogeneticcrisprsystemtoconnectwithandcontrolbiologicalinformationnetworks
AT pricilahauk aredoxbasedelectrogeneticcrisprsystemtoconnectwithandcontrolbiologicalinformationnetworks
AT gregoryfpayne aredoxbasedelectrogeneticcrisprsystemtoconnectwithandcontrolbiologicalinformationnetworks
AT williamebentley aredoxbasedelectrogeneticcrisprsystemtoconnectwithandcontrolbiologicalinformationnetworks
AT narendranathbhokisham redoxbasedelectrogeneticcrisprsystemtoconnectwithandcontrolbiologicalinformationnetworks
AT ericvanarsdale redoxbasedelectrogeneticcrisprsystemtoconnectwithandcontrolbiologicalinformationnetworks
AT kristinatstephens redoxbasedelectrogeneticcrisprsystemtoconnectwithandcontrolbiologicalinformationnetworks
AT pricilahauk redoxbasedelectrogeneticcrisprsystemtoconnectwithandcontrolbiologicalinformationnetworks
AT gregoryfpayne redoxbasedelectrogeneticcrisprsystemtoconnectwithandcontrolbiologicalinformationnetworks
AT williamebentley redoxbasedelectrogeneticcrisprsystemtoconnectwithandcontrolbiologicalinformationnetworks
_version_ 1721439668506984448