A redox-based electrogenetic CRISPR system to connect with and control biological information networks
Redox-responsive transcriptional regulators can enable user-specified electronic control over biological functions. Here the authors demonstrate electronic control of CRISPRa and CRISPRi using redox signalling.
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Nature Publishing Group
2020-05-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-020-16249-x |
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doaj-342e464f3acf40f68405ffc01b6bffe32021-05-16T11:12:03ZengNature Publishing GroupNature Communications2041-17232020-05-0111111210.1038/s41467-020-16249-xA redox-based electrogenetic CRISPR system to connect with and control biological information networksNarendranath Bhokisham0Eric VanArsdale1Kristina T. Stephens2Pricila Hauk3Gregory F. Payne4William E. Bentley5Biological Sciences Graduate Program—College of Computer, Mathematical and Natural Sciences, University of MarylandInstitute of Bioscience and Biotechnology Research, University of MarylandInstitute of Bioscience and Biotechnology Research, University of MarylandInstitute of Bioscience and Biotechnology Research, University of MarylandInstitute of Bioscience and Biotechnology Research, University of MarylandInstitute of Bioscience and Biotechnology Research, University of MarylandRedox-responsive transcriptional regulators can enable user-specified electronic control over biological functions. Here the authors demonstrate electronic control of CRISPRa and CRISPRi using redox signalling.https://doi.org/10.1038/s41467-020-16249-x |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Narendranath Bhokisham Eric VanArsdale Kristina T. Stephens Pricila Hauk Gregory F. Payne William E. Bentley |
spellingShingle |
Narendranath Bhokisham Eric VanArsdale Kristina T. Stephens Pricila Hauk Gregory F. Payne William E. Bentley A redox-based electrogenetic CRISPR system to connect with and control biological information networks Nature Communications |
author_facet |
Narendranath Bhokisham Eric VanArsdale Kristina T. Stephens Pricila Hauk Gregory F. Payne William E. Bentley |
author_sort |
Narendranath Bhokisham |
title |
A redox-based electrogenetic CRISPR system to connect with and control biological information networks |
title_short |
A redox-based electrogenetic CRISPR system to connect with and control biological information networks |
title_full |
A redox-based electrogenetic CRISPR system to connect with and control biological information networks |
title_fullStr |
A redox-based electrogenetic CRISPR system to connect with and control biological information networks |
title_full_unstemmed |
A redox-based electrogenetic CRISPR system to connect with and control biological information networks |
title_sort |
redox-based electrogenetic crispr system to connect with and control biological information networks |
publisher |
Nature Publishing Group |
series |
Nature Communications |
issn |
2041-1723 |
publishDate |
2020-05-01 |
description |
Redox-responsive transcriptional regulators can enable user-specified electronic control over biological functions. Here the authors demonstrate electronic control of CRISPRa and CRISPRi using redox signalling. |
url |
https://doi.org/10.1038/s41467-020-16249-x |
work_keys_str_mv |
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