Dissection and surgical approaches to the mouse jugular-nodose ganglia

Summary: The jugular-nodose ganglia contain the sensory peripheral neurons of the vagus nerve, linking visceral organs to the medulla oblongata. Accessing these ganglia in smaller animals without damaging the vascular and neural structures may be challenging, as ganglionic fibers imbed deeply into t...

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Main Authors:	Wenfei Han, Ivan E. de Araujo
Format:	Article
Language:	English
Published:	Elsevier 2021-06-01
Series:	STAR Protocols
Subjects:	Metabolism Microscopy Neuroscience
Online Access:	http://www.sciencedirect.com/science/article/pii/S2666166721001817

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spelling	doaj-3427d8aba24845c58529a38875dfd06e2021-06-21T04:25:18ZengElsevierSTAR Protocols2666-16672021-06-0122100474Dissection and surgical approaches to the mouse jugular-nodose gangliaWenfei Han0Ivan E. de Araujo1Nash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Corresponding authorNash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Pharmacology and Therapeutics Discovery Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Diabetes, Obesity and Metabolism Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USASummary: The jugular-nodose ganglia contain the sensory peripheral neurons of the vagus nerve, linking visceral organs to the medulla oblongata. Accessing these ganglia in smaller animals without damaging the vascular and neural structures may be challenging, as ganglionic fibers imbed deeply into the carotid sheath, and vagal parasympathetic fibers cross through the interior of the ganglia. We describe a practical protocol for locating and accessing the mouse jugular-nodose ganglia in vivo, including instructions for intraganglionic injections and postperfusion dissection.For complete details on the use and execution of this protocol, please refer to Han et al. (2018).http://www.sciencedirect.com/science/article/pii/S2666166721001817MetabolismMicroscopyNeuroscience
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Wenfei Han Ivan E. de Araujo
spellingShingle	Wenfei Han Ivan E. de Araujo Dissection and surgical approaches to the mouse jugular-nodose ganglia STAR Protocols Metabolism Microscopy Neuroscience
author_facet	Wenfei Han Ivan E. de Araujo
author_sort	Wenfei Han
title	Dissection and surgical approaches to the mouse jugular-nodose ganglia
title_short	Dissection and surgical approaches to the mouse jugular-nodose ganglia
title_full	Dissection and surgical approaches to the mouse jugular-nodose ganglia
title_fullStr	Dissection and surgical approaches to the mouse jugular-nodose ganglia
title_full_unstemmed	Dissection and surgical approaches to the mouse jugular-nodose ganglia
title_sort	dissection and surgical approaches to the mouse jugular-nodose ganglia
publisher	Elsevier
series	STAR Protocols
issn	2666-1667
publishDate	2021-06-01
description	Summary: The jugular-nodose ganglia contain the sensory peripheral neurons of the vagus nerve, linking visceral organs to the medulla oblongata. Accessing these ganglia in smaller animals without damaging the vascular and neural structures may be challenging, as ganglionic fibers imbed deeply into the carotid sheath, and vagal parasympathetic fibers cross through the interior of the ganglia. We describe a practical protocol for locating and accessing the mouse jugular-nodose ganglia in vivo, including instructions for intraganglionic injections and postperfusion dissection.For complete details on the use and execution of this protocol, please refer to Han et al. (2018).
topic	Metabolism Microscopy Neuroscience
url	http://www.sciencedirect.com/science/article/pii/S2666166721001817
work_keys_str_mv	AT wenfeihan dissectionandsurgicalapproachestothemousejugularnodoseganglia AT ivanedearaujo dissectionandsurgicalapproachestothemousejugularnodoseganglia
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Dissection and surgical approaches to the mouse jugular-nodose ganglia

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