Organophosphate flame retardants (OPFRs) induce genotoxicity in vivo: A survey on apoptosis, DNA methylation, DNA oxidative damage, liver metabolites, and transcriptomics

Background: As potential substitutes for polybrominated diphenyl ethers (PBDEs), organophosphate flame retardants (OPFRs) have been frequently detected in the environment. However, the genotoxicity induced by these OPFRs has rarely been described, and the results reported in previous studies are con...

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Bibliographic Details
Main Authors: Rui Chen, Rui Hou, Xiangsheng Hong, Saihong Yan, Jinmiao Zha
Format: Article
Language:English
Published: Elsevier 2019-09-01
Series:Environment International
Online Access:http://www.sciencedirect.com/science/article/pii/S0160412019308980