Pathway analysis of rare variants for the clustered phenotypes by using hierarchical structured components analysis
Abstract Backgrounds Recent large-scale genetic studies often involve clustered phenotypes such as repeated measurements. Compared to a series of univariate analyses of single phenotypes, an analysis of clustered phenotypes can be useful for substantially increasing statistical power to detect more...
Main Authors: | Sungyoung Lee, Sunmee Kim, Yongkang Kim, Bermseok Oh, Heungsun Hwang, Taesung Park |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-07-01
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Series: | BMC Medical Genomics |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12920-019-0517-4 |
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