Generation of a TALEN-mediated, p63 knock-in in human induced pluripotent stem cells

The expression of p63 in surface ectodermal cells during development of the cornea, skin, oral mucosa and olfactory placodes is integral to the process of cellular self-renewal and the maintenance of the epithelial stem cell status. Here, we used TALEN technology to generate a p63 knock-in (KI) huma...

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Bibliographic Details
Main Authors: Yuki Kobayashi, Ryuhei Hayashi, Andrew J. Quantock, Kohji Nishida
Format: Article
Language:English
Published: Elsevier 2017-12-01
Series:Stem Cell Research
Subjects:
p63
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506117302179