Interleukin-7 facilitates HIV-1 transmission to cervico-vaginal tissue ex vivo.

The majority of HIV-1 infections in women occur through vaginal intercourse, in which virus-containing semen is deposited on the cervico-vaginal mucosa. Semen is more than a mere carrier of HIV-1, since it contains many biological factors, in particular cytokines, that may affect HIV-1 transmission....

Full description

Bibliographic Details
Main Authors: Andrea Introini, Christophe Vanpouille, Andrea Lisco, Jean-Charles Grivel, Leonid Margolis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-02-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3567179?pdf=render