Disparate volumetric fluid shifts across cerebral tissue compartments with two different anesthetics

Abstract Background Large differences in glymphatic system transport—similar in magnitude to those of the sleep/wake cycle—have been observed during anesthesia with dexmedetomidine supplemented with low dose isoflurane (DEXM-I) in comparison to isoflurane (ISO). However, the biophysical and bioenerg...

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Bibliographic Details
Main Authors: Burhan O. Ozturk, Brittany Monte, Sunil Koundal, Feng Dai, Helene Benveniste, Hedok Lee
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Fluids and Barriers of the CNS
Subjects:
Online Access:https://doi.org/10.1186/s12987-020-00236-x