Symmetric neural progenitor divisions require chromatin-mediated homologous recombination DNA repair by Ino80

Chromatin mediates transcription and DNA repair. Here, the authors show distinct roles of chromatin remodeler INO80 in expression of YY1-regulated genes and repair of DNA breaks by homologous recombination, a DNA repair pathway important for symmetrically-dividing neural progenitors.

Bibliographic Details
Main Authors:	Jason M. Keil, Daniel Z. Doyle, Adel Qalieh, Mandy M. Lam, Owen H. Funk, Yaman Qalieh, Lei Shi, Nitesh Mohan, Alice Sorel, Kenneth Y. Kwan
Format:	Article
Language:	English
Published:	Nature Publishing Group 2020-07-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/s41467-020-17551-4

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spelling	doaj-340883430271499d8929db958f2df6452021-08-01T11:39:22ZengNature Publishing GroupNature Communications2041-17232020-07-0111111510.1038/s41467-020-17551-4Symmetric neural progenitor divisions require chromatin-mediated homologous recombination DNA repair by Ino80Jason M. Keil0Daniel Z. Doyle1Adel Qalieh2Mandy M. Lam3Owen H. Funk4Yaman Qalieh5Lei Shi6Nitesh Mohan7Alice Sorel8Kenneth Y. Kwan9Michigan Neuroscience Institute (MNI), University of MichiganMichigan Neuroscience Institute (MNI), University of MichiganMichigan Neuroscience Institute (MNI), University of MichiganMichigan Neuroscience Institute (MNI), University of MichiganMichigan Neuroscience Institute (MNI), University of MichiganMichigan Neuroscience Institute (MNI), University of MichiganMichigan Neuroscience Institute (MNI), University of MichiganMichigan Neuroscience Institute (MNI), University of MichiganMichigan Neuroscience Institute (MNI), University of MichiganMichigan Neuroscience Institute (MNI), University of MichiganChromatin mediates transcription and DNA repair. Here, the authors show distinct roles of chromatin remodeler INO80 in expression of YY1-regulated genes and repair of DNA breaks by homologous recombination, a DNA repair pathway important for symmetrically-dividing neural progenitors.https://doi.org/10.1038/s41467-020-17551-4
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Jason M. Keil Daniel Z. Doyle Adel Qalieh Mandy M. Lam Owen H. Funk Yaman Qalieh Lei Shi Nitesh Mohan Alice Sorel Kenneth Y. Kwan
spellingShingle	Jason M. Keil Daniel Z. Doyle Adel Qalieh Mandy M. Lam Owen H. Funk Yaman Qalieh Lei Shi Nitesh Mohan Alice Sorel Kenneth Y. Kwan Symmetric neural progenitor divisions require chromatin-mediated homologous recombination DNA repair by Ino80 Nature Communications
author_facet	Jason M. Keil Daniel Z. Doyle Adel Qalieh Mandy M. Lam Owen H. Funk Yaman Qalieh Lei Shi Nitesh Mohan Alice Sorel Kenneth Y. Kwan
author_sort	Jason M. Keil
title	Symmetric neural progenitor divisions require chromatin-mediated homologous recombination DNA repair by Ino80
title_short	Symmetric neural progenitor divisions require chromatin-mediated homologous recombination DNA repair by Ino80
title_full	Symmetric neural progenitor divisions require chromatin-mediated homologous recombination DNA repair by Ino80
title_fullStr	Symmetric neural progenitor divisions require chromatin-mediated homologous recombination DNA repair by Ino80
title_full_unstemmed	Symmetric neural progenitor divisions require chromatin-mediated homologous recombination DNA repair by Ino80
title_sort	symmetric neural progenitor divisions require chromatin-mediated homologous recombination dna repair by ino80
publisher	Nature Publishing Group
series	Nature Communications
issn	2041-1723
publishDate	2020-07-01
description	Chromatin mediates transcription and DNA repair. Here, the authors show distinct roles of chromatin remodeler INO80 in expression of YY1-regulated genes and repair of DNA breaks by homologous recombination, a DNA repair pathway important for symmetrically-dividing neural progenitors.
url	https://doi.org/10.1038/s41467-020-17551-4
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Symmetric neural progenitor divisions require chromatin-mediated homologous recombination DNA repair by Ino80

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