Glutamatergic Dysfunction and Synaptic Ultrastructural Alterations in Schizophrenia and Autism Spectrum Disorder: Evidence from Human and Rodent Studies

Glutamatergic Dysfunction and Synaptic Ultrastructural Alterations in Schizophrenia and Autism Spectrum Disorder: Evidence from Human and Rodent Studies

The correlation between dysfunction in the glutamatergic system and neuropsychiatric disorders, including schizophrenia and autism spectrum disorder, is undisputed. Both disorders are associated with molecular and ultrastructural alterations that affect synaptic plasticity and thus the molecular and...

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Bibliographic Details
Main Authors: Ahmed Eltokhi, Andrea Santuy, Angel Merchan-Perez, Rolf Sprengel
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:International Journal of Molecular Sciences
Subjects:
glutamatergic system
synaptic ultrastructure
schizophrenia
autism spectrum disorder
Online Access:https://www.mdpi.com/1422-0067/22/1/59

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