Interaction study of moxifloxacin with Cu(II) ion using square-wave voltammetry and its application in the determination in tablets
This work presents an electroanalytical method for the determination of moxifloxacin (MOXI) in tablets by its interaction with Cu(II) ion and subsequent electrochemical reduction at hang- ing mercury drop electrode (HMDE). A well-defined reduction peak at -0.21 V vs. Ag/AgCl in Phosphate buffer 0.04...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Universidade Estadual Paulista
2018-09-01
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| Series: | Eclética Química |
| Online Access: | https://revista.iq.unesp.br/ojs/index.php/ecletica/article/view/405 |
| Summary: | This work presents an electroanalytical method for the determination of moxifloxacin
(MOXI) in tablets by its interaction with Cu(II) ion and subsequent electrochemical reduction at hang-
ing mercury drop electrode (HMDE). A well-defined reduction peak at -0.21 V vs. Ag/AgCl in
Phosphate buffer 0.04 mol L -1 pH 8.0 was observed for the complex reduction MOXI-Cu(II), using
square-wave voltammetry (SWV). Using a 10 s of accumulation time at -0.40 V was found a limit
detection of 3.60x10 -8 mol l -1 . The obtained results have shown good agreement with those obtained by
spectrophotometric method. |
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| ISSN: | 1678-4618 |