A missense variant rs2585405 in clock gene PER1 is associated with the increased risk of noise-induced hearing loss in a Chinese occupational population

A missense variant rs2585405 in clock gene PER1 is associated with the increased risk of noise-induced hearing loss in a Chinese occupational population

Abstract Objective To investigate the potential association of cochlear clock genes (CRY1, CRY2, PER1, and PER2), the DNF gene (brain-derived neurotrophic factor), and the NTF3 gene (neurotrophin3) with susceptivity to noise-induced hearing loss (NIHL) among Chinese noise-exposed workers. Methods A...

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Bibliographic Details
Main Authors: Hao Chen, Xuexue Ding, Enmin Ding, Mengyao Chen, Huimin Wang, Guangzhi Yang, Baoli Zhu
Format: Article
Language:English
Published: BMC 2021-09-01
Series:BMC Medical Genomics
Subjects:
Cochlear clock genes
PER1
Polymorphism
Noise-induced hearing loss
Susceptibility
Online Access:https://doi.org/10.1186/s12920-021-01075-x

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