Reversible bone pain and symmetric bone scan uptake in a dialysis patient treated with cinacalcet: a case report

• Main Authors: Bottino Carla, Sancassani Rhea, Lenz Oliver, Fornoni Alessia
• Format: Article
• Language: English
• Published: BMC 2010-06-01
• Series: Journal of Medical Case Reports
• Online Access: http://www.jmedicalcasereports.com/content/4/1/191

<p>Abstract</p> <p>Introduction</p> <p>The medical management of secondary hyperparathyroidism in patients with end-stage renal disease involves a combination of dietary restrictions, phosphate binders, active vitamin D analogs, and calcimimetics.</p> <p>Case presentation</p> <p>We report the case of a 36-year-old Hispanic dialysis patient, originally from Cuba and now residing in the USA, who developed severe bone pain and muscle twitching after starting low dose cinacalcet, despite normal pre-dialysis ionized calcium and elevated parathyroid hormone. The clinical symptoms correlated with increased symmetrical uptake on bone scan that resolved rapidly upon discontinuation of cinacalcet.</p> <p>Conclusion</p> <p>Cinacalcet may induce severe bone pain and a unique bone scan uptake pattern in hemodialysis patients.</p>