Safety and acceptability of clozapine and risperidone in progressive multiple sclerosis: a phase I, randomised, blinded, placebo-controlled trial

Safety and acceptability of clozapine and risperidone in progressive multiple sclerosis: a phase I, randomised, blinded, placebo-controlled trial

Objective Because clozapine and risperidone have been shown to reduce neuroinflammation in humans and mice, the Clozapine and Risperidone in Progressive Multiple Sclerosis (CRISP) trial was conducted to determine whether clozapine and risperidone are suitable for progressive multiple sclerosis (pMS)...

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Bibliographic Details
Main Authors: Anne C La Flamme, David Abernethy, Dalice Sim, Liz Goode, Michelle Lockhart, David Bourke, Imogen Milner, Toni-Marie Garrill, Purwa Joshi, Eloise Watson, Duncan Smyth, Bronwen Connor
Format: Article
Language:English
Published: BMJ Publishing Group 2020-07-01
Series:BMJ Neurology Open
Online Access:https://neurologyopen.bmj.com/content/2/1/e000060.full

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