Clustering of activated microglia occurs before the formation of dystrophic neurites in the evolution of Aβ plaques in Alzheimer’s disease.

Alzheimer’s disease (AD) is a late-onset disease that has proved difficult to model. Microglia are implicated in AD, but reports vary on precisely when and how in the sequence of pathological changes they become involved. Here, post-mortem human tissue from two differentially affected regions of the...

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Bibliographic Details
Main Authors: Patrick Jarmo Paasila, Danielle S Davies, Greg T Sutherland, Claire Goldsbury
Format: Article
Language:English
Published: University of Münster / Open Journals System 2020-08-01
Series:Free Neuropathology
Subjects:
Online Access:https://www.uni-muenster.de/Ejournals/index.php/fnp/article/view/2845