SPARCoC: a new framework for molecular pattern discovery and cancer gene identification.
It is challenging to cluster cancer patients of a certain histopathological type into molecular subtypes of clinical importance and identify gene signatures directly relevant to the subtypes. Current clustering approaches have inherent limitations, which prevent them from gauging the subtle heteroge...
Main Authors: | Shiqian Ma, Daniel Johnson, Cody Ashby, Donghai Xiong, Carole L Cramer, Jason H Moore, Shuzhong Zhang, Xiuzhen Huang |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2015-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4359112?pdf=render |
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